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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are usually focused on practical aspects of the study design, such as recruitment and consent, adherence, and the use of routinely available equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which used various investigators and participants from different geographical regions. This kind of heterogeneity is required for practical trials to be valid, 프라그마틱 무료체험 메타 and 프라그마틱 게임 it also reduces the chance of bias in the results. However, too much heterogeneity can result in problems with the design of the trial.

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The purpose of pragmatic trials is to mimic real-life scenarios and to achieve maximum validity externally. They are usually ordered by policymakers and practitioners to help guide their decisions. They can also be a great way to identify the causal relationship between an intervention and its results. They should, however, not, be used to replace the need for explanation studies.

The idea of pragmatism is controversial and there are concerns regarding whether pragmatic trials could be used to replace explanation tests or if they are an alternative to them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which prove a physiological or clinical hypothesis, and pragmatic trials that inform the policy and practice of. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the elements of a practical study, including recruitment, design, implementation of the intervention and its follow-up.

There is a positive increase in the number of pragmatic trials that are published. A recent Medline search using the terms naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs) produced 34 articles, shown in red in Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatism. It is important to note that the majority of these studies were conducted in primary care settings.