Bio Fire: A Simple Definition

The BIOFIRE System and Your Immune System

The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare professionals to choose the appropriate test the first time. Patients benefit from quicker diagnosis and more targeted therapy. Clinicians benefit from better antibiotic stewardship. Labs gain efficiency and cost savings.

The BioFire Pneumonia Plus Panel (PN panel) analyzes native sputum (including mini-BAL) as well as endotracheal sludge and bronchoalveolar slurries (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials within an hour.

Respiratory

The burning of biomass (wood, plants and other organic materials) produces gaseous pollutants and fine particles that negatively impact the respiratory system. Additionally, the environmental issues caused by forest bioethanol fires, such as droughts, can be potentiated by climate change, which can increase their negative impact on human health.

In the United States, wildfire smoke has been linked to respiratory illnesses, including asthma, COPD and lung cancer. Additionally, this kind of air pollution is an underlying risk factor for cardiovascular diseases and a significant contributor to the burden of illness in the most vulnerable populations that include those who are of lower socioeconomic status (SES).

Wildfires have led to unhealthy levels of air pollution built in bioethanol fireplace several communities during the COVID-19 epidemic. However, the public health response to this environmental issue has been sporadic and mostly focused on communicating regarding symptom management. This gap in knowledge is concerning considering the evidence of potential health risks from continued exposure to smoke and other causes of poor air quality.

Researchers are currently assessing the best ways to protect public's health during any future events of this nature. NIH is funding research into this crucial public health issue through the BLUE CORAL study as well as its successor, FIRE CORAL.

For the first time, a prospective cohort study will examine long-term effects resulting from exposure to smoke from wildfires as well as other sources. FIRE CORAL recruits adult participants who are hospitalized for COVID-19 index episodes and who speak English or Spanish, but are not pregnant. The Fire Coral protocol includes a battery in-person assessments that objectively assess pulmonary function testing and lung imaging, as well as functional assessment.

The lungs are particularly sensitive to the effects of smoke and other particles since they can trigger or worsen chronic respiratory conditions such as emphysema, asthma and COPD and increase the risk of contracting pneumonia. There are a variety of steps that can be taken to stop or lessen the negative health effects from short-term exposures to smoke, corner bioethanol fireplace which includes avoiding outdoor activities when possible and using the EPA's "N95" mask, which is designed to catch fine particles.

Smoke can also cause irritation to the eyes and throat, and cause the nose to run. To reduce the symptoms the lungs need to be flushed by drinking plenty of fluids and taking medications that decrease inflammation, such as corticosteroids.

Bloodstream

The bloodstream is the first line of defense against germs that enter your system. Dendritic cells, which are special cells, are like your fire department's call center; they gather antigens (molecules that trigger an immune response) from germs that are invading your body and then release proteins that signal other white blood cells to to fight them. The white blood cell counts, differentials and band cells were elevated during firefighters' firefighting shifts, as compared to levels after strenuous physical exertion with no firefighting.

Skin

Dermatologists were concerned that the smoke and ash from the California wildfires could have an adverse effect on the skin of those who were exposed to them. Maria Wei is a graduate student at the University of California, Irvine. She studies how extreme wildfire pollution affects the skin. Her research was published on April 22, 2012 in Scientific Reports.

The study of Wei shows that the temperature of the skin changes depending on the length of time that the body is exposed. It can take up to two hours for the skin of a person to reach its "flash point"--the moment at which it begins to burn and then turns ashy. It's crucial not to be close to a fire or campfire, and you should always wear protective clothing when going outside in a humid or hot day.

Forest fires will continue to occur, despite the steps implemented to reduce the risk of fires from causing pollution. Wei is predicting that the number of people suffering the consequences of wildfires will increase as climate change causes more and more forests to burn. This means that more people will need to wear hats and long sleeves and thick moisturizers.

The air pollution from wildfires can exacerbate atopic skin dermatitis, which is a condition that causes itchy skin in a lot of people. The particles in smoke can clog up pores and cause atopic skin to become worse.

Another issue is that atopic dermatitis is known to make people more sensitive to UV light, which can be aggravated by wildfire smoke. This can result in people looking for tanning salons and tannish with less protection.

While a fire and ice facial may reduce the effects of atopic skin dermatitis, it's not recommended for anyone who has an open wound or rash on their face. This treatment is not recommended for people with active acne, or if you are pregnant or nursing. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa, ethanol fireplace burner (privatehd.Org) is an intensive, results-driven facial that bridges the gap between a mild facial and a peel without requiring any downtime. It's designed to smooth the skin, alleviate the appearance of rosacea, lessen acne scarring, reduce lines and wrinkles, and stimulate cell renewal. It's a fantastic treatment that will give you radiant skin.

Infections

The human body is comprised of a complex set of organs and tissues that work together to protect us against infection. Infections can be caused by microorganisms, such as parasites, viruses and bacteria that invade healthy cells, causing them to multiply uncontrollably. If this happens, your immune system may respond with symptoms of illness. These symptoms could include a runny nose to an upset stomach, but can also include an increase in fever, swelling of lymph glands, or an scratch. The type of infection and its location can impact the symptoms.

Infections can be spread in a variety of ways, but they are most often spread through airborne droplets that remain after a sniff or cough. Bacterial diseases such as tuberculosis, strep throat, meningococcal disease, and Legionnaires disease spread through this method, along with certain viral infections such as the common cold and influenza. Certain infections caused by bacteria, such as skin infections and sexually transmitted diseases (STIs) like gonorrhea or chlamydia are transmitted by contact with infected tissue or mucous membranes as well as indirect contact with surfaces that are contaminated. Some bacterial infections are spread by insects like ticks, bio-Ethanol fire fleas, or mosquitoes.

Some parasites and viruses are small enough to penetrate your bloodstream and infect your cells which can lead to serious diseases like the common cold and AIDS. Fungi can cause a variety of skin ailments such as ringworm, athlete's foot, while some are a threat to the lungs and nervous system, such as the rabies virus.

The BioFire PN Panel utilizes our unique FilmArray technology to detect a comprehensive list of pathogens responsible for upper respiratory infections in sputum and samples of bronchoalveolar fluid. The kit includes a reagent bag that includes all the chemistry required to perform reverse transcription, nested multiplex PCR, and detection with a single machine. It's a simple solution to aid clinicians in identifying and treat patients with different respiratory symptoms. This test has received an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.